Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

DNA replication is a tightly controlled process that copies the genetic code, allowing its instructions to be conveyed from one generation of cells to the next. In diseases like cancer, these ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...

For the first time, scientists have captured how new antiviral drugs halt the herpes virus in real time as it tries to ...

In a recent study published in PLOS Pathogens, researchers reviewed the existing knowledge on the mechanisms through which deoxyribonucleic acid (DNA) tumor viruses (DTVs) evade the antiviral immunity ...

Naked mole-rats are one of nature's most extraordinary creatures. These burrowing rodents can live for up to 37 years, around ten times longer than relatives of a similar size. But what is the secret ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...