The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...
Calcium is one of the most important minerals for our body, playing a key role in maintaining bone health, supporting muscle function, and even regulating nerve transmission. Despite its importance, ...
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