Stimulated emission depletion (STED) microscopy is one of the family of super-resolution techniques developed to allow imaging beyond the normal diffraction limit of optical microscopy. The principle ...

The marker molecule can withstand the STED beam for a relatively long time, which allows time-lapse imaging of the live subject. Sample preparation is much easier for an optical microscope than a ...

Researchers have developed an AI framework revolutionizing microscopy by autonomously designing experiments. Named XLuminA, the platform optimizes processes 10,000 times faster than traditional ...

Artistic visualization of XLuminA's automated optical discovery process. The setup shows laser beams being guided through a network of optical elements including beam splitters, spatial light ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2024.240035 discusses multiplexed stimulated emission depletion nanoscopy for multi-color live-cell long-term imaging. In the field of ...

Novel developments also focus on quick and high-speed AFM to improve temporal resolution. 2 The combination of AFM with optical microscopy has expanded the number of possible applications, ...

Researchers achieved nanometer-scale resolution without requiring a dark state, expanding super-resolution imaging to non-fluorescent molecules and non-optical waves. The findings published in Nature ...

Leica Microsystems has unveiled TauSTED Xtend, a development of the company's TauSTED super-resolution platform intended to allow multicolor live cell imaging at nanoscale resolution. The platform ...

Fluorescence light microscopy techniques offer several advantages when imaging biological samples, including high image contrast, good labeling specificity, multicolor, and three dimensional (3D) ...