Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...

In this report I describe a new protein, defined by a monoclonal antibody, which is associated with vimentin filaments in a variety of cultured cells and in skeletal muscle. By immunofluorescence it ...

Vimentin intermediate filaments are generally present in mesenchymal cells. Vimentin is found not only in eukaryotic cells, but also in bacteria, where it helps to form the cytoskeleton. Vimentin is ...

The protein filament vimentin provides healthy cartilage with the mechanical strength and flexibility necessary to resist stress, according to a study published in the Journal of Orthopaedic Research.

This is a preview. Log in through your library . Abstract The coding region of the hamster desmin gene was fused to the 5′ flanking sequences of the hamster vimentin gene and introduced into the germ ...

Scientists have discovered that the small molecule withaferin-A simultaneously targets two intermediate filaments, GFAP and vimentin, which are implicated in reactive gliosis, a damaging biological ...

A defective protein explains why a failure in protein degradation would lead to the massive aggregations of a class of filaments that disrupt the functioning of neurons of children with the rare, ...

Intermediate filaments (IFs) are assembled from fibrous proteins that exhibit a central α-helical rod domain with a conserved substructure. This rod domain facilitates the formation of dimeric ...

Just as the human body has a skeleton to give it structure and support, a cell has a cytoskeleton to give it shape and stability. Some of the main structures that make up a cell’s cytoskeleton are ...

However, the molecular events by which heat shock transduces signals into cellular responses such as a transient blockage of protein synthesis, changes in nuclear and other organelle structures and ...

There are three main kinds of cytoskeletal filaments: microfilaments, microtubules, and intermediate filaments in Eukaryotic cells. Intermediate filaments help to provide structure to cells, and are ...