The cytoskeleton, an intricate network of protein filaments, motor proteins, and cross-linkers, largely determines the mechanical properties of cells. Among the three filamentous components, F-actin, ...

Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...

We previously demonstrated that truncated desmoplakin I (DP I) molecules containing the carboxyl terminus specifically coalign with and disrupt both keratin and vimentin intermediate filament (IF) ...

Scientists have discovered that the small molecule withaferin-A simultaneously targets two intermediate filaments, GFAP and vimentin, which are implicated in reactive gliosis, a damaging biological ...

Maintaining the shape of the cell, creating proper internal structure, guiding organelles and pulling chromosomes apart during mitosis are some of the important functions of the cytoskeleton. The ...

Just as the skeleton and muscles move the human body and hold its shape, all the cells of the body are stabilised and moved by a cellular skeleton. Unlike our skeleton, this cellular skeleton is a ...

Just as the human body has a skeleton to give it structure and support, a cell has a cytoskeleton to give it shape and stability. Some of the main structures that make up a cell’s cytoskeleton are ...

These are profile miRNAs that control cancer metastasis with Abcam’s Firefly particle technology. Abcam provides custom miRNA panel design to provide users with an assay customized to their ...

Most biological cells have a fixed place in an organism. However, cells can become mobile and move through the body. This happens, for example, during wound healing or when tumour cells divide ...

A recent study has found that extracellular vimentin can bind to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in vitro, and antibodies against vimentin can decrease ...