Let's go a little deeper into how the diffusion process works: At timestep T (the first step of the reverse-diffusion inference process), we sample noise from a known prior distribution.

Jul 11, 2023 · We demonstrate the power and generality of the method, called RoseTTAFold diffusion (RFdiffusion), by experimentally characterizing the structures and functions of …

Dec 3, 2025 · Today we are releasing RFdiffusion3 as open-source software. This state-of-the-art AI model for biodesign is capable of generating new proteins that interact with any type of …

Jul 16, 2025 · Explore the documentation here: https://sites.google.com/omsf.io/rfdiffusion. Help us improve this resource! Want another Rosetta Commons tool documented? Reach out …

May 29, 2024 · To accommodate the unique characteristics of RF signals, we first introduce a novel Time-Frequency Diffusion theory to enhance the original diffusion model, enabling it to …

Jul 11, 2023 · We have developed a guided diffusion model for generating new proteins called RFdiffusion. With prior design methods, tens of thousands of molecules may have to be tested …

Jul 20, 2025 · The field of biology is experiencing a significant advancement with the introduction of RFdiffusion, a type of artificial intelligence. This technology represents a leap forward in our …

Apr 10, 2025 · Our latest deep-learning model, RFdiffusion2, can be used to generate enzyme backbones with custom active sites from simple descriptions of chemical reactions. This …

Dec 5, 2023 · RoseTTAFold Diffusion (RF Diffusion) RF Diffusion is an AI-based tool for protein backbone design

We demonstrate the power and generality of the method, called RoseTTAFold diffusion (RFdiffusion), by experimentally characterizing the structures and functions of hundreds of …